Chimeric Streptavidins as Host Proteins for Artificial Metalloenzymes
نویسندگان
چکیده
منابع مشابه
Artificial metalloenzymes: proteins as hosts for enantioselective catalysis.
Enantioselective catalysis is one of the most efficient ways to synthesize high-added-value enantiomerically pure organic compounds. As the subtle details which govern enantioselection cannot be reliably predicted or computed, catalysis relies more and more on a combinatorial approach. Biocatalysis offers an attractive, and often complementary, alternative for the synthesis of enantiopure produ...
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Enzymatic and homogeneous catalysis offer complementary means to produce enantiopure products. Incorporation of achiral, biotinylated aminodiphosphine-rhodium complexes in (strept)avidin affords enantioselective hydrogenation catalysts. A combined chemogenetic procedure allows the optimization of the activity and the selectivity of such artificial metalloenzymes: the reduction of acetamidoacryl...
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The Mn(TpCPP)-Xln10A artificial metalloenzyme, obtained by non-covalent insertion of Mn(III)-meso-tetrakis(p-carboxyphenyl)porphyrin [Mn(TpCPP), 1-Mn] into xylanase 10A from Streptomyces lividans (Xln10A) as a host protein, was found able to catalyze the selective photo-induced oxidation of organic substrates in the presence of [Ru(bpy)3] as a photosensitizer and [Co(NH3)5Cl] as a sacrificial e...
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ژورنال
عنوان ژورنال: ACS Catalysis
سال: 2018
ISSN: 2155-5435,2155-5435
DOI: 10.1021/acscatal.7b03773